CLINICAL, MICROBIOLOGICAL, AND IMAGING CHARACTERISTICS OF INFECTIVE ENDOCARDITIS IN LATIN AMERICA: A SYSTEMATIC REVIEW

Clinical, Microbiological, and Imaging Characteristics of Infective Endocarditis in Latin America: A Systematic Review

Objectives: We aimed to describe the clinical, microbiological, and imaging characteristics of patients with infective endocarditis (IE) in studies from Latin America (LATAM).Methods: A systematic search through PubMed, EMBASE, LILACS, and SciELO from inception until February 2021 was conducted.We included observational studies that assessed adults

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Understanding the impact related to lifestyle interventions for people with dementia: A systematic review protocol.

There duospiritalis.com is growing evidence to suggest that lifestyle initiatives promote brain health and reduce dementia risk.However, there is comparatively limited research focused on lifestyle interventions among people living with dementia.Most recent systematic reviews of lifestyle interventions among people living with dementia centre on th

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The auto-inhibitory role of the EPAC hinge helix as mapped by NMR.

The cyclic-AMP binding domain (CBD) is the central regulatory unit of exchange proteins activated by cAMP (EPAC).The CBD maintains EPAC in a state of auto-inhibition in the absence of the allosteric effector, cAMP.When cAMP binds to the CBD such duospiritalis.com auto-inhibition is released, leading to EPAC activation.It has been shown that a key f

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